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EWTX - Edgewise Therapeutics, Inc.


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Edgewise Therapeutics, Inc. is a biopharmaceutical company focused on developing small molecule therapies aimed at treating musculoskeletal diseases. The company’s primary emphasis is on addressing genetically defined muscle disorders through innovative drug development. By leveraging cutting-edge science and precision medicine approaches, Edgewise seeks to provide targeted solutions for complex and challenging conditions affecting muscle function.

The company's lead product candidate, EDG-5506, is an orally administered small molecule designed to target the underlying causes of dystrophinopathies, including Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD). This candidate has successfully completed Phase 1 clinical trials, demonstrating its potential to significantly impact the treatment of these severe muscle-wasting diseases. EDG-5506 aims to correct the dysfunctional muscle proteins associated with these conditions, offering a promising new approach to managing dystrophinopathies.

In addition to EDG-5506, Edgewise Therapeutics is developing a robust pipeline of precision medicine candidates targeting key muscle proteins and modulators. This pipeline includes therapies designed to address a range of genetically defined muscle disorders, reflecting the company’s commitment to tailoring treatments to the specific genetic and molecular underpinnings of each condition. By focusing on precise molecular targets, Edgewise aims to enhance therapeutic efficacy and improve patient outcomes in the field of musculoskeletal diseases.

Founded in 2017 and headquartered in Boulder, Colorado, Edgewise Therapeutics operates at the forefront of biopharmaceutical innovation. The company's dedication to developing novel small molecule therapies underscores its mission to transform the treatment landscape for muscle diseases. Through its advanced research and development efforts, Edgewise is poised to make significant strides in addressing critical unmet needs and advancing the standard of care for patients with musculoskeletal disorders.

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