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SPHS - Sophiris Bio, Inc.

Sophiris Bio, Inc. logo Sophiris Bio, Inc. (SPHS) is a clinical-stage biopharmaceutical company that focuses on the development of therapeutics for the treatment of urological diseases. The company's lead product candidate is topsalysin (PRX302), a genetically modified recombinant protein that is designed to selectively target and destroy the prostate gland. It is being evaluated in a Phase 3 clinical trial for the treatment of localized prostate cancer.

In addition to topsalysin, Sophiris Bio has a pipeline of product candidates that target the treatment of other urological diseases such as benign prostatic hyperplasia (BPH) and chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). The company's pipeline includes PRX302 for the treatment of BPH, PRX321 for the treatment of CP/CPPS, and PRX718 for the treatment of high-grade non-muscle invasive bladder cancer.

Sophiris Bio is headquartered in La Jolla, California and was founded in 2002. The company's mission is to provide innovative therapies to patients suffering from urological diseases. Sophiris Bio's team is made up of experienced professionals in the biopharmaceutical industry, and the company has partnerships with leading researchers and clinical experts in the field of urology.

As of February 24, 2023, Sophiris Bio's stock is listed on the Nasdaq Global Market exchange and has a market capitalization of approximately $120 million. The company has recently announced positive results from its Phase 3 clinical trial of topsalysin for the treatment of localized prostate cancer, which has boosted investor confidence in the company's prospects. However, as a clinical-stage company, Sophiris Bio faces risks and uncertainties associated with the development of its product candidates, including the risk of failure in clinical trials, regulatory approvals, and competition from other companies.




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