Mesoblast Limited (MESO) is an Australian-based biotechnology company that focuses on developing innovative cellular medicines for various diseases such as cardiovascular diseases, oncology, inflammatory diseases, and orthopedic disorders. The company's products are based on mesenchymal lineage cells, which are cells that can develop into multiple cell types, including bone, cartilage, and muscle cells.
Mesoblast has several products in its pipeline, including remestemcel-L, which is used to treat acute graft-versus-host disease (aGVHD) in children, and rexlemestrocel-L, which is used to treat chronic heart failure. The company has also entered into a number of partnerships with other pharmaceutical companies to develop its products, including Novartis, Teva Pharmaceutical Industries, and Lonza Group.
Mesoblast has had a mixed financial performance, with periods of both growth and decline. The company has experienced some setbacks, such as the FDA's rejection of its drug candidate Ryoncil for the treatment of acute graft-versus-host disease in adults, which caused the company's stock to drop significantly. However, the company has also had some positive news, such as a $50 million investment from the pharmaceutical company Grunenthal and the announcement of positive clinical trial results for remestemcel-L.
Overall, Mesoblast is a company with a promising pipeline of innovative cellular medicines, but with the inherent risks associated with biotechnology companies, such as clinical trial failures and regulatory hurdles.
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